Search results for "Harmful algal bloom"

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Metal stresses modify soluble proteomes and toxin profiles in two Mediterranean strains of the distributed dinoflagellate Alexandrium pacificum

2022

WOS:000789651000009; HABs involving Alexandrium pacificum have been reported in metal-contaminated ecosystems, suggesting that this distributed species adapts to and/or can tolerate the effects of metals. Modifications in soluble proteomes and PST contents were characterized in two Mediterranean A. pacificum strains exposed to mono- or polymetallic stresses (zinc, lead, copper, cadmium). These strains were isolated from two anthropized locations: Santa Giusta Lagoon (Italy, SG C10-3) and the Tarragona seaport (Spain, TAR C5-4F). In both strains, metals primarily downregulated key photosynthesis proteins. Metals also upregulated other proteins involved in photosynthesis (PCP in both strains)…

ProteomicsEnvironmental EngineeringProteomeParalytic shellfish toxins[SDE.MCG]Environmental Sciences/Global Changeschemistry.chemical_elementmedicine.disease_causePhotosynthesiscomplex mixturesMicrobiologychemistry.chemical_compoundTar (tobacco residue)BiosynthesismedicineEnvironmental ChemistryWaste Management and DisposalEcosystemCadmiumbiologyStrain (chemistry)Harmful algal bloomToxinChemistryDinoflagellatebiology.organism_classificationPollutionADKMetalsDinoflagellida[SDE.BE]Environmental Sciences/Biodiversity and Ecology
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Synthetic Haptens and Monoclonal Antibodies to the Cyanotoxin Anatoxin‐a

2019

Early warning systems for monitoring toxic events may benefit from the availability of monoclonal antibodies enabling the sensitive and specific detection of anatoxin-a, a cyanotoxin involved in numerous cases of animal poisoning resulting from toxic algal blooms in freshwaters. Through the synthesis of three functionalized derivatives of anatoxin-a, we have succeeded in generating the first-ever reported immunoreagents (bioconjugates and antibodies) suitable for the development of immunoanalytical approaches aimed at rapid and onsite detection of this harmful cyanotoxin.

Specific detectionmedicine.drug_classHarmful Algal BloomEnzyme-Linked Immunosorbent AssayAnimal poisoningBiology010402 general chemistryMonoclonal antibody01 natural sciencesAlgal bloomCatalysisAnatoxin-aMicrobiologychemistry.chemical_compoundmedicineAnimalsCyanobacteria Toxins010405 organic chemistryAntibodies MonoclonalSerum Albumin BovineStereoisomerismGeneral ChemistryCyanotoxin0104 chemical scienceschemistrybiology.proteinCattleAntibodyHaptensHaptenTropanesAngewandte Chemie International Edition
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